发明申请
US20060142204A1 Pyrrolidine derivatives for use in treating heaptitis c virus infection
审中-公开
用于治疗heaptitis c病毒感染的吡咯烷衍生物
- 专利标题： Pyrrolidine derivatives for use in treating heaptitis c virus infection
- 专利标题（中）： 用于治疗heaptitis c病毒感染的吡咯烷衍生物
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申请号： US10534905申请日： 2003-10-09
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公开(公告)号： US20060142204A1公开(公告)日： 2006-06-29
- 发明人: Philippe Halfon , Chalom Sayada , Jean-Marc Feryn , Regis Perbost , Frederic Garzino , Michel Camplo , Jerome Courcambeck , Gerard Pepe
- 申请人： Philippe Halfon , Chalom Sayada , Jean-Marc Feryn , Regis Perbost , Frederic Garzino , Michel Camplo , Jerome Courcambeck , Gerard Pepe
- 申请人地址： FR Marseille
- 专利权人： GENOSCIENCE
- 当前专利权人： GENOSCIENCE
- 当前专利权人地址： FR Marseille
- 优先权： EP02292487.2 20021009
- 国际申请： PCT/IB03/04884 WO 20031009
- 主分类号： A61K38/05
- IPC分类号： A61K38/05 ; A61K38/04 ; C07K5/06 ; C07K5/04
摘要：
The present invention relates to novel hepatitis C virus (“HCV”) protease inhibitors or other flavivirus protease inhibitors having the general structure (I) or (II), pharmaceutical compositions containing one or more such inhibitors, methods for preparing such inhibitors, uses of these compounds to treat hepatitis C and related disorders together with their use for their activity towards NS3 serine protease, intermediary compounds for the method of preparation of said compounds and screening methods. The invention specifically discloses novel chemical compounds as inhibitors of the HCV serine protease.
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