发明申请
- 专利标题： Rho-kinase inhibitors
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申请号： US11354977申请日： 2006-02-16
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公开(公告)号： US20060142313A1公开(公告)日： 2006-06-29
- 发明人: Dhanaphalan Nagarathnam , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Uday Khire , Chunguang Wang , Barry Hart , Stephen Boyer , Olaf Weber , Mark Lynch
- 申请人： Dhanaphalan Nagarathnam , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Uday Khire , Chunguang Wang , Barry Hart , Stephen Boyer , Olaf Weber , Mark Lynch
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; A61K31/4709 ; C07D403/02
摘要：
Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
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