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发明申请
US20060143725A1 Method of expressing gene in transgenic birds using retrovirus vector and transgenic birds thus obtained 审中-公开
使用由此获得的逆转录病毒载体和转基因鸟类在转基因鸟中表达基因的方法

Method of expressing gene in transgenic birds using retrovirus vector and transgenic birds thus obtained
摘要：
The present invention has for its object to provide a G0 transgenic chimera bird which is introduced an antibody gene with a replication-defective retrovirus vector, and produces an antibody by expressing the transgene; a production method of an antibody which comprises recovering the antibody expressed by the produced G0 transgenic chimera bird; and a production method of a G0 transgenic chimera bird which comprises incubating a bird fertile egg, and injecting an embryo after and exclusive of a period immediately after the start of incubation with a retrovirus vector. That is, the present invention relates to a G0 transgenic chimera bird which is introduced an antibody gene with a replication-defective retrovirus vector, and produces an antibody by expressing a transgene.
摘要（中）：

本发明的目的是提供一种G0转基因嵌合体鸟，其通过复制缺陷型逆转录病毒载体引入抗体基因，并通过表达转基因产生抗体; 一种抗体的制备方法，其包括回收由所产生的G0转基因嵌合体鸟表达的抗体; 以及G0转基因嵌合体鸟的制造方法，其包括孵育鸟可育卵，并且在与逆转录病毒载体开始孵育后立即注射胚胎之后注射胚胎。 也就是说，本发明涉及一种G0转基因嵌合体鸟，其通过复制缺陷型逆转录病毒载体导入抗体基因，并通过表达转基因产生抗体。

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