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    Method of constructing transgenic bird using lentivirus vector and transgenic bird obtained thereby
    2.
    发明申请
    Method of constructing transgenic bird using lentivirus vector and transgenic bird obtained thereby 审中-公开
    使用慢病毒载体和由此获得的转基因鸟构建转基因鸟的方法

    公开(公告)号：US20060259997A1

    公开(公告)日：2006-11-16

    申请号：US10569268

    申请日：2004-08-27

    申请人： Shinji Iijima ,  Masamichi Kamihira ,  Kenichi Nishijima

    发明人： Shinji Iijima ,  Masamichi Kamihira ,  Kenichi Nishijima

    IPC分类号： A01K67/027 ,  C12N5/06 ,  C12N15/867

    CPC分类号： A01K67/0275 ,  A01K67/0271 ,  A01K2217/05 ,  A01K2227/30 ,  C12N15/86 ,  C12N2740/15043 ,  C12N2740/15045

    摘要： The present invention provides a lentivirus vector which comprises a coat protein containing VSV-G; a recombinant bird host which is constructed by infecting a bird host with the lentivirus vector; a method of constructing the same; a transgenic chimeric bird which is constructed by infection with the lentivirus vector and offspring thereof. The present invention also provides a method of constructing a G0 transgenic chimeric bird and offspring thereof which comprises infecting fertilized bird egg early embryos with a lentivirus vector comprising a coat protein containing VSV-G, and incubating the embryos; and a G0 transgenic chimeric bird and offspring thereof which is constructed by the method mentioned above. The present invention provides a transgenic bird which is constructed by infecting a bird early embryos with a lentivirus vector comprising a coat protein pseudotyped with VSV-G.

    摘要翻译： 本发明提供一种慢病毒载体，其包含含有VSV-G的外壳蛋白; 通过用慢病毒载体感染鸟类宿主构建的重组禽类宿主; 一种构建它的方法; 通过感染慢病毒载体及其后代构建的转基因嵌合鸟。 本发明还提供了构建G0转基因嵌合鸟及其后代的方法，其包括用含有VSV-G的外壳蛋白的慢病毒载体感染受精鸟卵早期胚胎，并培养胚胎; 和通过上述方法构建的G0转基因嵌合鸟及其后代。 本发明提供一种转基因鸟，其通过用包含用VSV-G假型包被的蛋白质的慢病毒载体感染鸟类早期胚胎而构建。

    Transgenic Bird And Method Of Constructing The Same
    4.
    发明申请
    Transgenic Bird And Method Of Constructing The Same 审中-公开
    转基因鸟及其构建方法

    公开(公告)号：US20070214511A1

    公开(公告)日：2007-09-13

    申请号：US10585693

    申请日：2004-11-05

    申请人： Takashi Yamashita ,  Takuya Shindo ,  Shinji Iijima ,  Masamichi Kamihira ,  Kenichi Nishijima

    发明人： Takashi Yamashita ,  Takuya Shindo ,  Shinji Iijima ,  Masamichi Kamihira ,  Kenichi Nishijima

    IPC分类号： A01K67/027 ,  C12N15/89 ,  C12N5/16 ,  C12P21/00 ,  C12Q1/68

    CPC分类号： C12N15/8509 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2227/30 ,  A01K2267/01

    摘要： The present invention provides a G1 transgenic bird or an offspring thereof by: incubating a fertilized avian egg, microinjecting, into the early embryo thereof at a stage except for and after the blastodermic stage just after egg laying, a replication-deficient retroviral vector coding for a useful protein, allowing the egg to hatch out to thereby obtain a G0 transgenic chimeric bird, and mating the G0 transgenic chimeric bird with another G0 transgenic chimeric bird or an offspring thereof or with a wild-type bird. The present invention is a G1 transgenic bird or an offspring thereof by: incubating a fertilized avian egg, microinjecting, into the early embryo thereof at a stage except for and after the blastodermic stage just after egg laying, a replication-deficient retroviral vector coding for a useful protein, allowing the egg to hatch out to thereby obtain a G0 transgenic chimeric bird, and mating the G0 transgenic chimeric bird with another G0 transgenic chimeric bird or an offspring thereof or with a wild-type bird.

    摘要翻译： 本发明通过以下方式提供G1转基因鸟或其后代：在产卵后的胚根期以外的阶段将受精禽卵孵育至其早期胚胎，将其编码为复制缺陷型逆转录病毒载体 一种有用的蛋白质，允许卵孵出，从而获得G0转基因嵌合鸟，并将G0转基因嵌合鸟与另一种G0转基因嵌合鸟或其后代或野生型鸟交配。 本发明是一种G1转基因鸟或其后代，其特征在于：在产卵后的胚根期以外的阶段将受精禽卵孵化至其早期胚胎，将其编码为复制缺陷型逆转录病毒载体 一种有用的蛋白质，允许卵孵出，从而获得G0转基因嵌合鸟，并将G0转基因嵌合鸟与另一种G0转基因嵌合鸟或其后代或野生型鸟交配。

    Solid state imaging device
    8.
    发明授权
    Solid state imaging device 失效
    固态成像装置

    公开(公告)号：US07705375B2

    公开(公告)日：2010-04-27

    申请号：US11584488

    申请日：2006-10-23

    申请人： Kenichi Nishijima ,  Toshihiro Kuriyama

    发明人： Kenichi Nishijima ,  Toshihiro Kuriyama

    IPC分类号： H01L29/00

    CPC分类号： H01L27/14812

    摘要： A solid state imaging device includes: a plurality of photoelectric conversion portions formed in a substrate in a matrix arrangement to convert light incident on light receiving portions into electricity; a plurality of vertical transfer registers for reading charges out of the photoelectric conversion portions and transferring the charges in the column direction; and a plurality of shunt interconnections formed above the vertical transfer electrodes in one-to-one correspondence with the columns of the photoelectric conversion portions to supply drive pulses to the corresponding vertical transfer electrodes. Each of the vertical transfer registers includes a vertical transfer channel formed in the substrate in one-to-one correspondence with a column of the photoelectric conversion portions and a plurality of vertical transfer electrodes formed above the vertical transfer channel. Each of the shunt interconnections is configured to surround the light receiving portions and having windows that expose the light receiving portions.

    摘要翻译： 一种固态成像装置，包括：多个光电转换部，其形成在基板上，矩阵状配置，将入射到受光部的光转换为电; 多个垂直传送寄存器，用于从光电转换部分读出电荷并在列方向上传送电荷; 以及多个分流互连，其形成在垂直传输电极上方，与光电转换部分的列一一对应，以向相应的垂直传输电极提供驱动脉冲。 每个垂直传送寄存器包括在基板中形成的垂直传输通道，其与光电转换部分的列一一对应，以及形成在垂直传送通道上方的多个垂直传输电极。 每个分流互连被配置为围绕光接收部分并且具有暴露光接收部分的窗口。

    Solid state imaging device
    9.
    发明申请
    Solid state imaging device 失效
    固态成像装置

    公开(公告)号：US20070182837A1

    公开(公告)日：2007-08-09

    申请号：US11584488

    申请日：2006-10-23

    申请人： Kenichi Nishijima ,  Toshihiro Kuriyama

    发明人： Kenichi Nishijima ,  Toshihiro Kuriyama

    IPC分类号： H04N9/083 ,  H04N3/14 ,  H04N5/335 ,  H04N9/04

    CPC分类号： H01L27/14812

    摘要： A solid state imaging device includes: a plurality of photoelectric conversion portions formed in a substrate in a matrix arrangement to convert light incident on light receiving portions into electricity; a plurality of vertical transfer registers for reading charges out of the photoelectric conversion portions and transferring the charges in the column direction; and a plurality of shunt interconnections formed above the vertical transfer electrodes in one-to-one correspondence with the columns of the photoelectric conversion portions to supply drive pulses to the corresponding vertical transfer electrodes. Each of the vertical transfer registers includes a vertical transfer channel formed in the substrate in one-to-one correspondence with a column of the photoelectric conversion portions and a plurality of vertical transfer electrodes formed above the vertical transfer channel. Each of the shunt interconnections is configured to surround the light receiving portions and having windows that expose the light receiving portions.

    摘要翻译： 一种固态成像装置，包括：多个光电转换部，其形成在基板上，矩阵状配置，将入射到受光部的光转换为电; 多个垂直传送寄存器，用于从光电转换部分读出电荷并在列方向上传送电荷; 以及多个分流互连，其形成在垂直传输电极上方，与光电转换部分的列一一对应，以向相应的垂直传输电极提供驱动脉冲。 每个垂直传送寄存器包括在基板中形成的垂直传输通道，其与光电转换部分的列一一对应，以及形成在垂直传送通道上方的多个垂直传输电极。 每个分流互连被配置为围绕光接收部分并且具有暴露光接收部分的窗口。

    Comparator circuit with current mirror
    10.
    发明授权
    Comparator circuit with current mirror 有权
    比较器电路与电流镜

    公开(公告)号：US08598914B2

    公开(公告)日：2013-12-03

    申请号：US13115358

    申请日：2011-05-25

    申请人： Kenichi Nishijima ,  Kouhei Yamada

    发明人： Kenichi Nishijima ,  Kouhei Yamada

    IPC分类号： H03K5/153

    CPC分类号： H03K5/2472

    摘要： A comparator circuit can achieve a reduction in current consumption with a simple configuration, and can suppress an increase in current consumption accompanying a rise in power source voltage. A current mirror circuit is connected to a power source, and gates of MOSFETs of the circuit are interconnected. An input signal is applied to a gate of an NMOSFET of the circuit. By determining the value of the signal with a constant voltage device, the voltage across a tail resistor is constant, even in the event that the power source voltage and the input signal change.

    摘要翻译： 比较器电路可以通过简单的配置实现电流消耗的降低，并且可以抑制伴随电源电压的上升的电流消耗的增加。 电流镜电路连接到电源，电路的MOSFET的栅极相互连接。 输入信号施加到电路的NMOSFET的栅极。 通过用恒压器件确定信号的值，即使在电源电压和输入信号发生变化的情况下，尾电阻两端的电压也是恒定的。