- 专利标题： Methods and compositions for treating and preventing infection using human interferon regulatory factor 3
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申请号： US11358007申请日： 2006-02-22
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公开(公告)号： US20060147421A1公开(公告)日： 2006-07-06
- 发明人: Paul Moore , Paula Pitha Rowe , Craig Rosen
- 申请人： Paul Moore , Paula Pitha Rowe , Craig Rosen
- 申请人地址： US MD Rockville US MD Baltimore
- 专利权人： Human Genome Sciences, Inc.,Johns Hopkins University
- 当前专利权人： Human Genome Sciences, Inc.,Johns Hopkins University
- 当前专利权人地址： US MD Rockville US MD Baltimore
- 主分类号： C07K14/715
- IPC分类号： C07K14/715 ; C07H21/04 ; C12P21/06 ; A61K48/00 ; C12N15/867
摘要：
The present invention relates to IRF3 polypeptides. In particular, isolated nucleic acid molecules are provided encoding human IRF3 protein. IRF3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods of gene therapy using polynucleotides encoding IRF3 polypeptides, fragments or variants to treat, prevent or ameliorate infectious diseases.
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