发明申请
US20060159701A1 Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
审中-公开
细菌ADP-核糖基化毒素的解毒突变体作为胃肠外辅助剂
- 专利标题: Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
- 专利标题(中): 细菌ADP-核糖基化毒素的解毒突变体作为胃肠外辅助剂
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申请号: US11367056申请日: 2006-03-02
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公开(公告)号: US20060159701A1公开(公告)日: 2006-07-20
- 发明人: Gail Barchfeld , Giuseppe Del Giudice , Rino Rappuoli
- 申请人: Gail Barchfeld , Giuseppe Del Giudice , Rino Rappuoli
- 申请人地址: US CA Emeryville
- 专利权人: Chiron Corporation
- 当前专利权人: Chiron Corporation
- 当前专利权人地址: US CA Emeryville
- 主分类号: A61K39/116
- IPC分类号: A61K39/116 ; A61K39/108
摘要:
The present invention provides parenteral adjuvants comprising detoxified mutants of bacterial ADP-ribosylating toxins, particularly those from pertussis (PT), cholera (CT), and heat-labile E. coli (LT).
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