发明申请
US20060159757A1 Pharmaceutical composition for controlled release of beta-lactam antibiotics in combination with beta-lactamase inhibitors
审中-公开
β-内酰胺抗生素与β-内酰胺酶抑制剂联合控制释放的药物组合物
- 专利标题： Pharmaceutical composition for controlled release of beta-lactam antibiotics in combination with beta-lactamase inhibitors
- 专利标题（中）： β-内酰胺抗生素与β-内酰胺酶抑制剂联合控制释放的药物组合物
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申请号： US11303516申请日： 2005-12-16
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公开(公告)号： US20060159757A1公开(公告)日： 2006-07-20
- 发明人: Keith Payne , Christian Kiera , Jennifer Dressman
- 申请人： Keith Payne , Christian Kiera , Jennifer Dressman
- 申请人地址： DE Goettingen
- 专利权人： NextPharma GmbH
- 当前专利权人： NextPharma GmbH
- 当前专利权人地址： DE Goettingen
- 优先权： DEDE102005000719.8 20050103
- 主分类号： A61K31/43
- IPC分类号： A61K31/43 ; A61K31/545 ; A61K9/26 ; A61K31/407
摘要：
The invention relates to a pharmaceutical composition containing a β-lactam antibiotic and/or a pharmaceutically tolerable salt thereof in the form of coated pellets that may optionally contain a β-lactamase inhibitor and/or a pharmaceutically tolerable salt thereof, some or all pellets comprising coatings that dissolve at different pH values depending on the composition of said coatings. This pharmaceutical composition allows the blood plasma level of the β-lactam antibiotic and/or a pharmaceutically tolerable salt thereof to remain above 2 μg/ml for at least 12 hours within a period of 24 hours if administered twice a day.
公开/授权文献
- US1349904A Alarm device 公开/授权日：1920-08-17
信息查询
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