发明申请
- 专利标题： Substituted phenyl methanone derivatives
- 专利标题（中）： 取代苯甲酮衍生物
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申请号： US11332999申请日： 2006-01-17
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公开(公告)号： US20060160788A1公开(公告)日： 2006-07-20
- 发明人: Synese Jolidon , Robert Narquizian , Roger Norcross , Emmanuel Pinard
- 申请人： Synese Jolidon , Robert Narquizian , Roger Norcross , Emmanuel Pinard
- 优先权： EP05100280.6 20050118
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; A61K31/4015 ; A61K31/397 ; C07D211/44 ; C07D207/02 ; C07D205/02
摘要：
The present invention relates to compounds of formula I wherein R1, R2, R3, n, and m, are as defined in the specification and to pharmaceutically acceptable acid addition salts thereof. These compounds are good inhibitors of the glycine transporter 1 (GlyT-1) and are useful for the treatment of CNS disorders such as schizophrenia, cognitive impairment, and Alzheimer's disease.
公开/授权文献
- US07790763B2 Substituted phenyl methanone derivatives 公开/授权日：2010-09-07
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