发明申请
US20060160884A1 Alkynyl-containing tryptophan derivative inhibitors of tace/matrix metalloproteinase
失效
Tace /基质金属蛋白酶的含炔基的色氨酸衍生物抑制剂
- 专利标题： Alkynyl-containing tryptophan derivative inhibitors of tace/matrix metalloproteinase
- 专利标题（中）： Tace /基质金属蛋白酶的含炔基的色氨酸衍生物抑制剂
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申请号： US11318701申请日： 2005-12-27
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公开(公告)号： US20060160884A1公开(公告)日： 2006-07-20
- 发明人: Kaapjoo Park , Jeremy Levin , Ariamala Gopalsamy
- 申请人： Kaapjoo Park , Jeremy Levin , Ariamala Gopalsamy
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/405
- IPC分类号： A61K31/405 ; C07D407/02 ; C07D209/18
摘要：
This invention provides compounds of Formula I, having the structure: that are useful in treating diseases or disorders mediated by TNF-α. The invention further provides methods for use of the compounds for treating such a disease or disorder or for alleviating symptoms thereof.
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