发明申请
US20060166214A1 Marker for detecting mesenchymal stem cell and method of distinguishing mesenchymal stem cell using the marker
审中-公开
用于检测间充质干细胞的标记和使用标记区分间充质干细胞的方法
- 专利标题： Marker for detecting mesenchymal stem cell and method of distinguishing mesenchymal stem cell using the marker
- 专利标题（中）： 用于检测间充质干细胞的标记和使用标记区分间充质干细胞的方法
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申请号： US10548681申请日： 2004-02-27
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公开(公告)号： US20060166214A1公开(公告)日： 2006-07-27
- 发明人: Yukio Kato , Koichiro Tsuji , Chika Koike
- 申请人： Yukio Kato , Koichiro Tsuji , Chika Koike
- 优先权： JP2003-63077 20030310
- 国际申请： PCT/JP04/02457 WO 20040227
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07H21/04
摘要：
The present invention provides a marker for detecting, separating/distinguishing a mesenchymal stem cell and a method for detecting, separating/distinguishing a mesenchymal stem cell by using the marker. A gene shown in the sequence listing is expressed specifically in a mesenchymal stem cell. The present invention comprises use of the gene as a marker for detecting mesenchymal stem cells. In addition, the present invention comprises a probe for detecting the mesenchymal stem cell marker gene and a PCR primer for amplifying the gene in a test cell in detecting the mesenchymal stem cell gene marker, and further comprises a polypeptide marker for detecting mesenchymal stem cells comprising a polypeptide wherein the mesenchymal stem cell marker gene of the present invention is expressed, an antibody for detecting the polypeptide marker which specifically binds to the polypeptide marker, and still further, a method for distinguishing and separating a mesenchymal stem cell by using a probe for detecting the mesenchymal stem cell marker gene, and an antibody which specifically binds to a polypeptide marker.
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