- 专利标题： Synthesis of himbacine analogs
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申请号： US11330935申请日： 2006-01-12
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公开(公告)号： US20060173189A1公开(公告)日： 2006-08-03
- 发明人: Tiruvettipuram Thiruvengadam , Tao Wang , Jing Liao , John Chiu , David Tsai , Hong-Chang Lee , Wenxue Wu , Xiaoyong Fu
- 申请人： Tiruvettipuram Thiruvengadam , Tao Wang , Jing Liao , John Chiu , David Tsai , Hong-Chang Lee , Wenxue Wu , Xiaoyong Fu
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 主分类号： C07D405/02
- IPC分类号： C07D405/02
摘要：
The present invention relates to an improved process for preparing himbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield on the desired enantiomer. An example of a step in the synthesis of such a himbacine analog is as follows:
公开/授权文献
- US07541471B2 Synthesis of himbacine analogs 公开/授权日：2009-06-02
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