公开(公告)号：US20130310899A1

公开(公告)日：2013-11-21

申请号：US13981584

申请日：2012-01-24

Applicant: David Tsai ,  John William Morley ,  Gregg Jorgen Suaning ,  Nigel Hamilton Lovell

Inventor： David Tsai ,  John William Morley ,  Gregg Jorgen Suaning ,  Nigel Hamilton Lovell

IPC: A61N1/36 ,  A61N1/05

CPC classification number: A61N1/36046 ,  A61N1/0543

Abstract: A method of neural stimulation is described for maintaining the responsiveness of electrically excitable cells to repeated electrical stimulation. A stimulating signal (23) is applied to the electrically excitable cells. The stimulating signal is repeatedly applied (26, 29, 32, 35) with a progressively increasing signal strength. A quiescent period (44) may be interleaved between bursts (43, 45) of stimulation. The electrically excitable cells may be retinal cells.

Abstract translation: 描述了一种神经刺激方法，用于维持电可激发细胞对反复电刺激的反应性。 刺激信号（23）被施加到电可激发细胞。 刺激信号被重复地施加（26,29,32,35），信号强度逐渐增加。 静止周期（44）可以在刺激的脉冲串（43,45）之间进行交织。 可电激活细胞可以是视网膜细胞。

公开(公告)号：US08300159B2

公开(公告)日：2012-10-30

申请号：US12765847

申请日：2010-04-22

Applicant: Shin-Gwo Shiue ,  David Tsai

Inventor： Shin-Gwo Shiue ,  David Tsai

IPC: G02F6/1335

CPC classification number: G03B21/006 ,  G03B21/2033 ,  H04N9/3152 ,  H04N9/3173

Abstract: A pico projector includes a light-emitting diode module, collimators, a lens array, magnification lenses, a reflection mirror, a polarizing beam splitter, an LCoS (light crystal on silicon) panel, and an image lens module, wherein the light-emitting diode module emits red, green, and blue lights. The collimators convert light from the light-emitting diode module into collimated light. The lens array homogenizes the collimated light. The magnification lenses magnify the homogenized light from the lens array with a predetermined ratio to be projected onto the LCoS panel. The reflection mirror changes direction of the light path. The polarizing beam splitter allows for transmission of a horizontal polarization light component and reflects a vertical polarization light component. The LCoS panel reflects and modulates the light to form an optic signal. The image lens module includes, in sequence, positive, positive, negative, positive, and positive lenses to project the optical signal to a screen.

Abstract translation: 微型投影仪包括发光二极管模块，准直仪，透镜阵列，放大透镜，反射镜，偏振分束器，LCoS（硅晶体）面板和图像透镜模块，其中发光 二极管模块发出红色，绿色和蓝色指示灯。 准直器将来自发光二极管模块的光转换为准直光。 透镜阵列使准直光均匀化。 放大透镜以预定比例将来自透镜阵列的均匀化光放大到投影到LCoS面板上。 反射镜改变光路的方向。 偏振分束器允许透射水平偏振光分量并反射垂直偏振光分量。 LCoS面板反映并调制光线以形成光信号。 图像透镜模块依次包括正，正，负，正和正透镜，以将光信号投影到屏幕。

公开(公告)号：US20120112429A1

公开(公告)日：2012-05-10

申请号：US12940269

申请日：2010-11-05

Applicant: Kun-Jie Wang ,  Rong-Jin Liang ,  David Tsai

Inventor： Kun-Jie Wang ,  Rong-Jin Liang ,  David Tsai

IPC: B62K19/00

CPC classification number: B62K3/04 ,  B62K19/18 ,  B62K2015/001

Abstract: A detachable top tube apparatus includes two tubes, two spring-biased detents, two hooks, two latches and an elastic element. The tubes are telescopically connected to each other. Each of the spring-biased detents is connected to a related one of the tubes. Each of the hooks includes a portion inserted in a related one of the tubes. Each of the latches each including two wings pivotally connected to a related one of the tubes between a releasing position and a locking position. In the releasing position, each of the latches allows a portion of a bicycle to be hooked by and unhooked from the related hook. In the locking position, each of the latches retains the portion of the bicycle hooked by the related hook. The elastic element interconnects the tubes.

Abstract translation: 可拆卸的顶管装置包括两个管，两个弹簧偏置的棘爪，两个钩，两个闩锁和一个弹性元件。 管彼此伸缩连接。 每个弹簧偏置的棘爪连接到相关的一个管中。 每个钩包括插入相关一个管中的部分。 每个闩锁每个包括两个翼，在释放位置和锁定位置之间枢转地连接到相关的一个管。 在释放位置中，每个闩锁允许自行车的一部分与相关钩钩挂并脱钩。 在锁定位置，每个闩锁保持骑自行车钩钩的部分。 弹性元件将管相互连接。

公开(公告)号：US20120069251A1

公开(公告)日：2012-03-22

申请号：US12886579

申请日：2010-09-21

Applicant: SHIN-GWO SHIUE ,  David Tsai

Inventor： SHIN-GWO SHIUE ,  David Tsai

IPC: G02F1/13363

CPC classification number: H04N9/3111 ,  G02B27/283 ,  G03B21/006 ,  H04N9/3173

Abstract: A dual-panel micro reflective liquid crystal projection device is provided for improving brightness of projected image, including a set of two reflective liquid crystal panels respectively arranged at top side and right side of a polarizing beam splitter so that a light beam emitting from a light source located at bottom side of the beam splitter is received and split by the beam splitter into a horizontal polarization component and a vertical polarization component, which are then respectively reflected and modulated by the two reflective panels into vertically polarized light and horizontal polarized light for simultaneously transmitting identical image signals to a projection system arranged at left side of the beam splitter to thereby double the brightness of the image projected onto a screen.

Abstract translation: 提供了一种双面微反射型液晶投影装置，用于提高投射图像的亮度，包括分别布置在偏振分束器的顶侧和右侧的两组反射液晶面板，使得从光发射的光束 位于分束器底部的光源被分束器接收并分离成水平偏振分量和垂直偏振分量，然后分别由两个反射板反射和调制成垂直偏振光和水平偏振光同时 将相同的图像信号发送到布置在分束器的左侧的投影系统，从而将投影到屏幕上的图像的亮度加倍。

公开(公告)号：US20110261274A1

公开(公告)日：2011-10-27

申请号：US12765847

申请日：2010-04-22

Applicant: SHIN-GWO SHIUE ,  David Tsai

Inventor： SHIN-GWO SHIUE ,  David Tsai

IPC: G02F1/13363

CPC classification number: G03B21/006 ,  G03B21/2033 ,  H04N9/3152 ,  H04N9/3173

Abstract: A pico projector includes a light-emitting diode module, collimators, a lens array, magnification lenses, a reflection mirror, a polarizing beam splitter, an LCoS (light crystal on silicon) panel, and an image lens module, wherein the light-emitting diode module emits red, green, and blue lights. The collimators convert light from the light-emitting diode module into collimated light. The lens array homogenizes the collimated light. The magnification lenses magnify the homogenized light from the lens array with a predetermined ratio to be projected onto the LCoS panel. The reflection mirror changes direction of the light path. The polarizing beam splitter allows for transmission of a horizontal polarization light component and reflects a vertical polarization light component. The LCoS panel reflects and modulates the light to form an optic signal. The image lens module includes, in sequence, positive, positive, negative, positive, and positive lenses to project the optical signal to a screen.

Abstract translation: 微型投影仪包括发光二极管模块，准直仪，透镜阵列，放大透镜，反射镜，偏振分束器，LCoS（硅晶体）面板和图像透镜模块，其中发光 二极管模块发出红色，绿色和蓝色指示灯。 准直器将来自发光二极管模块的光转换为准直光。 透镜阵列使准直光均匀化。 放大透镜以预定比例将来自透镜阵列的均匀化光放大到投影到LCoS面板上。 反射镜改变光路的方向。 偏振分束器允许透射水平偏振光分量并反射垂直偏振光分量。 LCoS面板反映并调制光线以形成光信号。 图像透镜模块依次包括正，正，负，正和正透镜，以将光信号投影到屏幕。

公开(公告)号：US20100122958A1

公开(公告)日：2010-05-20

申请号：US12270954

申请日：2008-11-14

Applicant: David Tsai

Inventor： David Tsai

IPC: B62H3/06

CPC classification number: B62H3/04

Abstract: A bicycle parking rack comprises a base member provided on the ground and including a first flat portion and a second flat portion respectively defined at first and second ends thereof and attach the ground, and with a wheel of a bicycle disposed between the first and second flat portions; and a support member including a coupled portion formed on a first end thereof and detachably coupling to the base member and a holding portion formed on a second end thereof and extending from the coupled portion, and with the coupled portion provided between the first and second flat portions.

Abstract translation: 一种自行车停放架包括一个设置在地面上的底座，它包括一个第一平坦部分和一个分别限定在其第一端和第二端的第二平坦部分，并附着在地面上，并且一个自行车车轮设置在第一和第二平面之间 部分 以及支撑构件，其包括形成在其第一端上并且可拆卸地联接到所述基座构件的联接部分和形成在其第二端上并从所述联接部分延伸的保持部分，并且所述联接部分设置在所述第一和第二平面 部分。

公开(公告)号：US20090116204A1

公开(公告)日：2009-05-07

申请号：US11979339

申请日：2007-11-01

Applicant: Jake Chen ,  David Tsai

Inventor： Jake Chen ,  David Tsai

IPC: H05K1/18 ,  H05K3/30

CPC classification number: H01G4/38 ,  H05K1/141 ,  H05K2201/042 ,  H05K2201/09063 ,  H05K2201/10015 ,  H05K2201/10409 ,  H05K2201/2036 ,  Y10T29/4913

Abstract: This invention is about the capacitor assembly improvement of electrical circuit system, including a central partitioning board, its surface has connecting hole installed through conductive component, both sides are distributed with insertion slots; first base board installed with sleeve hole connecting to one end of conductive component and an insertion hole corresponding to the insertion slot, its one side is soldered with multiple capacitors; and second base board, having a sleeve hole connecting to the other end of the conductive component and the insertion hole corresponding to the insertion slot, one side is soldered with multiple capacitors; thus the conductive component is inserted through central partitioning board and assemble the first and second base boards to both ends of the conductive component, to replace cable layout to form electrical connectivity, so that the problem of electrical circuit system of prior art having noise and high assembly cost can be overcome.

Abstract translation: 本发明是关于电路系统的电容器组件改进，包括中央分隔板，其表面具有通过导电部件安装的连接孔，两侧分布有插槽; 第一基板安装有与导电部件的一端连接的套筒孔和与插槽相对应的插入孔，其一侧用多个电容器焊接; 和第二基板，具有连接到导电部件的另一端的套筒孔和对应于插入槽的插入孔，一侧焊接有多个电容器; 因此导电部件通过中央分隔板插入，并将第一和第二基板组装到导电部件的两端，以取代电缆布局以形成电连接性，从而具有噪声高的现有技术的电路系统的问题 组装成本可以克服。

公开(公告)号：US20060266717A1

公开(公告)日：2006-11-30

申请号：US10908734

申请日：2005-05-24

Applicant: David Tsai

Inventor： David Tsai

IPC: A47F7/00

CPC classification number: B62H3/00

Abstract: A rack is disclosed for regulating the parking of bicycles. The rack includes a base that provides flexibility in length and at least one pair of restraints installed on the base. The base includes a first lateral tube, a second lateral tube and at least one pair of transverse tubes. The first lateral tube includes a central portion and two ends extending from the central portion. The second lateral tube includes a central portion and two ends extending from the central portion. Each transverse tube includes a first end connected to one of the ends of the first lateral tube and a second end connected to one of the ends of the second lateral tube. The pair of restraints is installed on the pair of transverse tubes.

Abstract translation: 公开了用于调节自行车停放的架子。 机架包括提供长度灵活性的基座和至少一对安装在基座上的约束。 基座包括第一横向管，第二侧管和至少一对横向管。 第一侧管包括中心部分和从中心部分延伸的两个端部。 第二侧管包括中心部分和从中心部分延伸的两个端部。 每个横管包括连接到第一侧管的一个端部的第一端和连接到第二侧管的一个端部的第二端。 一对约束装置安装在一对横管上。

公开(公告)号：US06720311B2

公开(公告)日：2004-04-13

申请号：US10145682

申请日：2002-05-14

Applicant: David Tsai

Inventor： David Tsai

IPC: A61K3808

CPC classification number: C07K14/4747 ,  A61K33/30 ,  A61K38/1741 ,  C07K14/71

Abstract: This invention characterizes the specific peptide fragment derived from specially prepared zinc charged fetuin and a method of preparation thereof, wherein the fragment was found to contain an apoptosis-inducing activity. Specifically, the amino acid sequence of this peptide is H-T-F-S-G-V-A-S-V-E and correlates to amino acid no. 300-309 of fetuin, referred to herein as Fetuin Peptide Fragment (FPF 300-09). FPF 300-09 strongly induced apoptosis in LNCaP (prostate cancer) and HT-29 (colon cancer) cells without affecting CCD 18 Co (normal colon) cells. The in vitro tissue culture study demonstrated that the FPF 300-09 is more potent than the parent molecule (full-length zinc charged fetuin) in inducing apoptosis. FPF 300-09 has a LD50 of 0.3-0.4 &mgr;M, while the LD50 for zinc-charged fetuin is 3-10 &mgr;M.

Abstract translation: 本发明的特征在于特别制备的加入锌的胎球蛋白的特异性肽片段及其制备方法，其中发现该片段含有凋亡诱导活性。 具体地说，该肽的氨基酸序列是H-T-F-S-G-V-A-S-V-E，与氨基酸编号相关。 300-309的胎球蛋白，在本文中称为胎儿蛋白肽片段（FPF 300-09）。 FPF 300-09强烈诱导LNCaP（前列腺癌）和HT-29（结肠癌）细胞凋亡，而不影响CCD 18 Co（正常结肠）细胞。 体外组织培养研究表明，FPF 300-09在诱导细胞凋亡中比​​母体分子（全长锌带电球蛋白）更有效。 FPF 300-09的LD50为0.3-0.4微米，而锌电荷胎球蛋白的LD50为3-10微米。

公开(公告)号：US06258779B1

公开(公告)日：2001-07-10

申请号：US09414136

申请日：1999-10-07

Applicant: David Tsai ,  Jenny Yu

Inventor： David Tsai ,  Jenny Yu

IPC: A61K3816

CPC classification number: A61K33/30 ,  A61K38/1741 ,  C07K14/4747 ,  C07K14/71 ,  Y10S514/908 ,  Y10S530/827 ,  Y10S530/828

Abstract: The present invention provides the methods to isolate the proteins specifically induced apoptosis (programmed cell death) in prostate cancer cells (LNCAP), leukemia cells (HL-60), and breast cancer cells (MCF-70), but without effect in normal human lung fibroblast cells (CCD 39 Lu). P-1 has no effect on breast cancer cells. Five proteins have been isolated from the conditioned media of culture cells: (1) Apogen P-1: the proteins (Apogen P-1a, Apogen P-1b and Apogen P-1c) isolated from the conditioned medium of XC cells are able to induce apoptosis in prostate cancer cells (LNCAP) without effect in normal human lung fibroblast (CCD 39 Lu), colon cancer (T84), breast cancer (MCF-7) and leukemia (HL-60) cells. (2) Apogen P-2: the protein isolated from the conditioned medium of C3H1OT1/2 cells is able to induce apoptosis in prostate cancer cells (LNCAP) and breast cancer (MCF-7) without effect in normal human lung fibroblast (CCD 39 Lu) and colon cancer (T84) cells. (3) Apogen L: the protein isolated from the conditioned medium of XC cells is able to induce apoptosis in leukemia cells (HL-60), and breast cancer (MCF-7) without effect in normal human lung fibroblast (CCD 39 Lu), colon cancer (T84) and prostate cancer (LNCAP) cells. The isolated protein Apogen P-2 is at least in part comprised of bovine fetuin. When properly prepared, fetuin is able to induce apoptosis in leukemia cells (HL-60), prostate cancer (LNCaP and PC-3) cells, colon cancer (Colo 205) cells, breast cancer (MCF-7) cells, and lung cancer (Calu-1) cells. The in vivo tests done with fetuin have shown an increased life span for mice bearing leukemia. The invention may lead to the discovery of a novel class of anticancer drug that aims at prostate cancer, breast cancer, leukemia and other cancers by inducing apoptosis in cancer cells without affecting normal cells.