发明申请
- 专利标题: Transgenic fibrinogen
- 专利标题(中): 转基因纤维蛋白原
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申请号: US11040117申请日: 2005-01-24
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公开(公告)号: US20060174357A1公开(公告)日: 2006-08-03
- 发明人: William Velander , Susan Lord , William Drohan , Henryk Lubon , John Johnson , Christopher Russell
- 申请人: William Velander , Susan Lord , William Drohan , Henryk Lubon , John Johnson , Christopher Russell
- 专利权人: Virginia Tech. Intellectual Properties,American National Red Cross,University of North Carolina at Chapel Hill
- 当前专利权人: Virginia Tech. Intellectual Properties,American National Red Cross,University of North Carolina at Chapel Hill
- 主分类号: A01K67/027
- IPC分类号: A01K67/027 ; C07K14/75
摘要:
A transgenic, non-human mammalian animal is capable of expressing a heterologous gene for human or other recombinant physiologically functional fibrinogen holoprotein or individual subunit chain polypeptides thereof or a modified or fusion fibrinogen in mammary glands of the animals and secreting the expressed product into a body fluid. Methodology employing such a mammal yields recombinant physiologically functional fibrinogens, subunit chain polypeptides thereof, and modified or fusion fibrinogens.
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