发明申请
US20060194870A1 Compound having anti-hcv activity and process for producing the same
有权
具有抗hcv活性的化合物及其制备方法
- 专利标题: Compound having anti-hcv activity and process for producing the same
- 专利标题(中): 具有抗hcv活性的化合物及其制备方法
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申请号: US10563089申请日: 2004-07-09
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公开(公告)号: US20060194870A1公开(公告)日: 2006-08-31
- 发明人: Masayuki Sudoh , Takuo Tsukuda , Miyako Masubuchi , Kenichi Kawasaki , Takeshi Murata , Fumio Watanabe , Hiroshi Fukuda , Susumu Komiyama , Tadakatsu Hayase
- 申请人: Masayuki Sudoh , Takuo Tsukuda , Miyako Masubuchi , Kenichi Kawasaki , Takeshi Murata , Fumio Watanabe , Hiroshi Fukuda , Susumu Komiyama , Tadakatsu Hayase
- 专利权人: CHUGAI SEIYAKU KABUSHIKI KAISHA
- 当前专利权人: CHUGAI SEIYAKU KABUSHIKI KAISHA
- 优先权: JP2003-272420 20030709
- 国际申请: PCT/JP04/09803 WO 20040709
- 主分类号: A61K31/385
- IPC分类号: A61K31/385 ; A61K31/335
摘要:
The object of the present invention is to provide a compound useful for the prevention and treatment of viral infectious diseases, and particularly liver diseases caused by HCV infection due to its having a high degree of replication inhibitory activity against HCV, its production method, an intermediate compound useful for its production and a pharmaceutical composition containing these compounds, and the present invention relates to a compound represented by the formula (I): (wherein A represents —(CH2)n—, etc.; B represents —(C═O)—, etc.; D represents —(CH2)m—R′, etc.; E represents a hydrogen atom, etc.; G represents —(CH2)p-J, etc.; bond Q represents a single bond or double bond; and R1, R2 and R3 may be the same or different and each represent a hydrogen atom, etc.), a prodrug thereof or a pharmaceutically acceptable salt thereof.
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