发明申请
- 专利标题: Biointerface membranes incorporating bioactive agents
- 专利标题(中): 包含生物活性剂的生物界面膜
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申请号: US11416825申请日: 2006-05-03
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公开(公告)号: US20060198864A1公开(公告)日: 2006-09-07
- 发明人: Mark Shults , James Brauker , Victoria Carr-Brendel , Mark Tapsak , Dubravka Markovic
- 申请人: Mark Shults , James Brauker , Victoria Carr-Brendel , Mark Tapsak , Dubravka Markovic
- 主分类号: A61F13/00
- IPC分类号: A61F13/00
摘要:
A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.