发明申请
US20060199838A1 Substituted N-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies
有权
取代的N-芳基苯甲酰胺和相关化合物用于治疗淀粉样蛋白病和突触核蛋白病
- 专利标题： Substituted N-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies
- 专利标题（中）： 取代的N-芳基苯甲酰胺和相关化合物用于治疗淀粉样蛋白病和突触核蛋白病
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申请号： US11328748申请日： 2006-01-09
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公开(公告)号： US20060199838A1公开(公告)日： 2006-09-07
- 发明人: Alan Snow , Beth Nguyen , Thomas Lake , Gerardo Castillo , Manfred Weigele
- 申请人： Alan Snow , Beth Nguyen , Thomas Lake , Gerardo Castillo , Manfred Weigele
- 主分类号： A61K31/46
- IPC分类号： A61K31/46 ; C07D457/02 ; A61K31/165
摘要：
Substituted n-aryl benzamides, related compounds and their pharmaceutically acceptable derivatives, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, including Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment are provided.
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