A decoder of a digital-to-analog converter is disclosed. In the present invention, the gamma voltage selection is controlled by a reduced number of NMOS and PMOS transistors according to the characteristic of the NMOS and PMOS transistor, such that the layout area of the switch array is reduced. Moreover, a N-type buried diffusion (BDN) layer and a P-type buried diffusion (BDP) layer are adopted to replace the contacts in the layout of conventional decoder, such that the layout can be simplified and the bump pad pitch thereof can be decreased.