发明申请
- 专利标题: Formulations of anthraquinone derivatives
- 专利标题(中): 蒽醌衍生物的配方
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申请号: US11433545申请日: 2006-05-15
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公开(公告)号: US20060205820A1公开(公告)日: 2006-09-14
- 发明人: William Denny , Laurence Patterson , Gavin Halbert , Steven Ford
- 申请人: William Denny , Laurence Patterson , Gavin Halbert , Steven Ford
- 申请人地址: GB London
- 专利权人: BTG International Limited
- 当前专利权人: BTG International Limited
- 当前专利权人地址: GB London
- 优先权: GB0206255.2 20020315
- 主分类号: C07C239/16
- IPC分类号: C07C239/16 ; A61K31/135
摘要:
A compound of formula (I): in which A is a C alkylene group with a chain length between NH and N(O)R′R″ of at least 2 carbon atoms and R′ and R″ are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C2-4 dihydroxyalkyl groups, or R′ and R″ together are a C2-6 alkylene group, is formulated so that upon dissolution in aqueous solution the pH of the solution is in the range of 5 to 9. The compound may be in the form of salt with a physiologically acceptable acid having a pKa in the range of −3.0 (minus 3.0) to 9.0.
公开/授权文献
- US07276537B2 Formulations of anthraquinone derivatives 公开/授权日:2007-10-02
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