发明申请
- 专利标题： Compounds for the treatment of proliferative disorders
- 专利标题（中）： 用于治疗增殖性疾病的化合物
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申请号： US11355922申请日： 2006-02-16
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公开(公告)号： US20060217389A1公开(公告)日： 2006-09-28
- 发明人: Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 申请人： Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; A61K31/501 ; A61K31/497 ; A61K31/4709 ; A61K31/4439 ; A61K31/426 ; A61K31/42
摘要：
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
公开/授权文献
- US07884094B2 Compounds for the treatment of proliferative disorders 公开/授权日：2011-02-08