发明申请
- 专利标题： Methods and compositions for modulating the activity of PDE5
- 专利标题（中）： 调节PDE5活性的方法和组合物
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申请号： US10352534申请日： 2003-01-28
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公开(公告)号： US20060222647A1公开(公告)日： 2006-10-05
- 发明人: Joseph Beavo , Jackie Corbin , Kenneth Ferguson , Sharron Francis , Ann Kadlecek , Linda McAllister-Lucas , Kate Loughney , William Sonnenburg , Melissa Thomas , Sergei Rybalkin
- 申请人： Joseph Beavo , Jackie Corbin , Kenneth Ferguson , Sharron Francis , Ann Kadlecek , Linda McAllister-Lucas , Kate Loughney , William Sonnenburg , Melissa Thomas , Sergei Rybalkin
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K38/54 ; A61K39/395
摘要：
The present invention provides agents such as agonists, antibodies, antagonists or inhibitors to modulate the activity of PDE5 proteins. These compositions and methods are useful for the diagnosis or treatment of conditions associated with the presence, the deficiency, altered levels, or altered activity of PDE5 proteins.
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