发明申请
- 专利标题： Crystalline form of a quinolinone-carboxamide compound
- 专利标题（中）： 喹啉酮 - 甲酰胺化合物的结晶形式
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申请号： US11398119申请日： 2006-04-05
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公开(公告)号： US20060229332A1公开(公告)日： 2006-10-12
- 发明人: Paul Fatheree , S. Turner , Adam Goldblum , Robert Chao , Daniel Genov
- 申请人： Paul Fatheree , S. Turner , Adam Goldblum , Robert Chao , Daniel Genov
- 专利权人： Theravance, Inc.
- 当前专利权人： Theravance, Inc.
- 主分类号： A61K31/46
- IPC分类号： A61K31/46 ; C07D451/02
摘要：
The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with 5-HT4 receptor activity, and processes useful for preparing such crystalline salt forms.
公开/授权文献
- US07728004B2 Crystalline form of a quinolinone-carboxamide compound 公开/授权日：2010-06-01
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