- 专利标题: Inhibitors of p38
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申请号: US11298324申请日: 2005-12-08
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公开(公告)号: US20060235014A1公开(公告)日: 2006-10-19
- 发明人: Guy Bemis , Francesco Salituro , John Duffy , John Cochran , Edmund Harrington , Mark Murko , Keith Wilson , Michael Su , Vincent Galullo
- 申请人: Guy Bemis , Francesco Salituro , John Duffy , John Cochran , Edmund Harrington , Mark Murko , Keith Wilson , Michael Su , Vincent Galullo
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; A61K31/53 ; A61K31/519 ; C07D487/04
摘要:
The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.
公开/授权文献
- US07365072B2 Inhibitors of p38 公开/授权日:2008-04-29
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