发明申请
- 专利标题： Phenylpyridazine derivatives as ligands for gaba receptors
- 专利标题（中）： 苯基哒嗪衍生物作为gaba受体的配体
-
申请号： US10524173申请日： 2003-08-04
-
公开(公告)号： US20060235021A1公开(公告)日： 2006-10-19
- 发明人: Wesley Blackaby , Peter Blurton , Frank Burkamp , Stephen Fletcher , Andrew Jennings , Richard Lewis , Angus Macleod , Leslie Street , Steve Thomas , Monique Van Niel , Kevin Wilson
- 申请人： Wesley Blackaby , Peter Blurton , Frank Burkamp , Stephen Fletcher , Andrew Jennings , Richard Lewis , Angus Macleod , Leslie Street , Steve Thomas , Monique Van Niel , Kevin Wilson
- 优先权： GB0218874.6 20020813; GB0229591.3 20021219
- 国际申请： PCT/GB03/03376 WO 20030804
- 主分类号： A61K31/501
- IPC分类号： A61K31/501 ; C07D403/02 ; A61K31/50
摘要：
A class of 4-phenylpyridazine derivatives of Formula (I), being selective ligands for GABAA receptors, in particular having high affinity for the α2 and/or α3 and or α5 subunit thereof, are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.
信息查询
IPC分类:
