发明申请
US20060239978A1 Gene expressed specifically in dopamine-producing neuron precursor cells after termination of division
失效
在分裂终止后，特异性表达多巴胺产生神经元前体细胞的基因
- 专利标题： Gene expressed specifically in dopamine-producing neuron precursor cells after termination of division
- 专利标题（中）： 在分裂终止后，特异性表达多巴胺产生神经元前体细胞的基因
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申请号： US10532264申请日： 2003-10-21
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公开(公告)号： US20060239978A1公开(公告)日： 2006-10-26
- 发明人: Yasuko Nakagawa , Yuichi Ono , Yoshima Sakamoto , Eri Mizuhara , Tomoya Nakatani , Yoshimi Takai
- 申请人： Yasuko Nakagawa , Yuichi Ono , Yoshima Sakamoto , Eri Mizuhara , Tomoya Nakatani , Yoshimi Takai
- 申请人地址： JP TOKYO 112-8088
- 专利权人： EISAI CO., LTD.
- 当前专利权人： EISAI CO., LTD.
- 当前专利权人地址： JP TOKYO 112-8088
- 优先权： JP2002-307573 20021022
- 国际申请： PCT/JP03/13420 WO 20031021
- 主分类号： A61K35/30
- IPC分类号： A61K35/30 ; C12Q1/68 ; G01N33/567 ; C07H21/04 ; C12N5/08 ; C07K14/705 ; C07K16/28
摘要：
A novel gene 65B13 expressed specifically and transiently in dopaminergic neuron precursor cells immediately after cell cycle exit was obtained by the present invention. The cellular expression of 65B13 can be used as an index to select cells that are suitable in terms of their safety, survival rate, and network formation ability, for transplant therapy of neurodegenerative diseases such as Parkinson's disease.
公开/授权文献
- US07622270B2 Methods of isolating dopaminergic neuron precursor cells 公开/授权日：2009-11-24
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