发明申请
- 专利标题: Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof
- 专利标题(中): 稠合杂环衍生物,含有它们的药物组合物及其医药用途
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申请号: US10551648申请日: 2004-03-24
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公开(公告)号: US20060247179A1公开(公告)日: 2006-11-02
- 发明人: Nobuhiko Fushimi , Shigeru Yonekubo , Hideyuki Muranaka , Hiroaki Shiohara , Hirotaka Teranishi , Kazuo Shimizu , Fumiaki Ito , Masayuki Isaji
- 申请人: Nobuhiko Fushimi , Shigeru Yonekubo , Hideyuki Muranaka , Hiroaki Shiohara , Hirotaka Teranishi , Kazuo Shimizu , Fumiaki Ito , Masayuki Isaji
- 优先权: JP2003-97152 20030331
- 国际申请: PCT/JP04/04009 WO 20040324
- 主分类号: A61K31/7052
- IPC分类号: A61K31/7052 ; C07H17/02
摘要:
The present invention provides fused heterocyclic derivatives represented by the general formula: wherein R1 represents H, halogen, OH, etc.; R2 represents H, halogen or an alkyl group; R3 and R4 represent H, OH, halogen, etc.; Q represents alkylene, etc.; ring A represents aryl or heteroaryl; and G represents , or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exhibit an excellent inhibitory activity in human SGLT and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications or obesity, pharmaceutical compositions comprising the same, and pharmaceutical uses thereof.
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