- 专利标题: Inhibitors for use in hemostasis
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申请号: US11479928申请日: 2006-06-29
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公开(公告)号: US20060252692A1公开(公告)日: 2006-11-09
- 发明人: Gerald Lasser , Paul Bishop , Joachim Fruebis , Woerner Meehan
- 申请人: Gerald Lasser , Paul Bishop , Joachim Fruebis , Woerner Meehan
- 专利权人: ZymoGenetics, Inc.
- 当前专利权人: ZymoGenetics, Inc.
- 主分类号: A61K38/39
- IPC分类号: A61K38/39
摘要:
The present invention relates to peptide, polynucleotide and fusion proteins for use as inhibitors in hemostasis. These inhibitors are members of the family of proteins bearing a collagen-like domain and a globular domain. The inhibitors are useful for promoting blood flow in the vasculature by reducing thrombogenic and complement activity. The inhibitors are also useful for pacify collagenous surfaces and modulating wound healing.
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