公开(公告)号：US20060252692A1

公开(公告)日：2006-11-09

申请号：US11479928

申请日：2006-06-29

申请人： Gerald Lasser ,  Paul Bishop ,  Joachim Fruebis ,  Woerner Meehan

发明人： Gerald Lasser ,  Paul Bishop ,  Joachim Fruebis ,  Woerner Meehan

IPC分类号： A61K38/39

CPC分类号： A61K38/49 ,  A61K38/1709 ,  A61K2300/00

摘要： The present invention relates to peptide, polynucleotide and fusion proteins for use as inhibitors in hemostasis. These inhibitors are members of the family of proteins bearing a collagen-like domain and a globular domain. The inhibitors are useful for promoting blood flow in the vasculature by reducing thrombogenic and complement activity. The inhibitors are also useful for pacify collagenous surfaces and modulating wound healing.