- 专利标题: Substituted pyrazolopyrimidines, methods for the production thereof, use of the same for controlling pathogenic fungi, and agents containing said compounds
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申请号: US10558251申请日: 2004-05-27
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公开(公告)号: US20060258685A1公开(公告)日: 2006-11-16
- 发明人: Olivier Wagner , Thomas Grote , Carsten Blettner , Markus Gewehr , Wassilios Grammenos , Andreas Gypser , Bernd Muller , Joachim Rheinheimer , Peter Schafer , Frank Schieweck , Anja Schwogler , Jordi Blasco , Alan Akers , John-Bryan Speakman , Michael Rack , Reinhard Stierl , Maria Scherer , Ulrich Schofl , Siegfried Strathmann
- 申请人: Olivier Wagner , Thomas Grote , Carsten Blettner , Markus Gewehr , Wassilios Grammenos , Andreas Gypser , Bernd Muller , Joachim Rheinheimer , Peter Schafer , Frank Schieweck , Anja Schwogler , Jordi Blasco , Alan Akers , John-Bryan Speakman , Michael Rack , Reinhard Stierl , Maria Scherer , Ulrich Schofl , Siegfried Strathmann
- 优先权: DE103252444 20030603; DE103359605 20030804; DE1020040059101 20040205
- 国际申请: PCT/EP04/05694 WO 20040527
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; C07D487/04
摘要:
The invention relates to substituted pyrazolopyrimidines of formula (I) wherein the substituents have the following designations: L represents halogen, alkyl, halogenalkyl, alkenyl, alkoxy, amino, NHR, NR2, cyano, S(═O)nA1 or C(═O)A2, R representing alkyl or alkylcarbonyl, A1 representing hydrogen, hydroxy, alkyl, alkylamino or dialkylamino, n representing 0, 1 or 2, and A2 representing alkenyl, alkoxy, halogenalkoxy or one of the groups cited for A1; m represents 0 or 1 to 5; R1 represents alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, alkadienyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl, phenyl, naphthyl, or a five-membered to ten-membered saturated, partially unsaturated or aromatic heterocycle containing between one and four heteroatoms from the group O, N or S; and R2 represents hydrogen or one of the groups cited for R1. Together with the nitrogen atom to which they are bonded, R1 and R2 can form a five-membered to six-membered ring that can be interrupted by an atom from the groups O, N and S, and R1 and/or R2 can also be substituted according to the description. Furthermore, in formula (I): X represents halogen, cyano, OH, alkyl, alkoxy or halogenalkoxy; Y represents a five-membered to ten-membered saturated, partially unsaturated or aromatic heterocycle according to the description, or a group X or another group according to the description; p represents 1 or 2, the groups Y being potentially different when p=2; and p represents 0, when X is according to the description. The invention also relates to methods and intermediate products for producing said compounds, agents containing the same, and the use thereof for controlling phytopathogenic fungi.
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