发明申请
- 专利标题: BIR domain binding compounds
- 专利标题(中): BIR结构域结合化合物
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申请号: US11434166申请日: 2006-05-16
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公开(公告)号: US20060264379A1公开(公告)日: 2006-11-23
- 发明人: Scott Jarvis , Alain Boudreault , Patrick Bureau , James Jaquith , Alain Laurent , Delphine Labit
- 申请人: Scott Jarvis , Alain Boudreault , Patrick Bureau , James Jaquith , Alain Laurent , Delphine Labit
- 主分类号: C07K5/06
- IPC分类号: C07K5/06 ; A61K38/05
摘要:
The present invention is directed towards an isomer, an enantiomer, a diastereoisomer, or a tautomer of a pyrrolidine compound represented by Formula I: in which the substituents R1, R1a, R2, R2a, R3, A and Q are defined herein; or a prodrug, or a salt thereof, and which bind to IAP BIR domains. In particular, the compounds are useful in treating proliferative disorders such as cancer
公开/授权文献
- US07772177B2 BIR domain binding compounds 公开/授权日:2010-08-10