- 专利标题： Tubulin inhibitor and process for its preparation
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申请号： US11451078申请日： 2006-06-12
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公开(公告)号： US20060281760A1公开(公告)日： 2006-12-14
- 发明人: David Blum , Yanzhong Wu , Jean Schmid , Timothy Doyle , Jay Afragola
- 申请人： David Blum , Yanzhong Wu , Jean Schmid , Timothy Doyle , Jay Afragola
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： C07D403/04
- IPC分类号： C07D403/04 ; A61K31/506
摘要：
The invention provides 6-chloro-5-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-2-pyrazin-2-yl-N-[(1S)-2,2,2-trifluoro-1-methylethyl]pyrimidin-4-amine hemifumarate which is a tubulin inhibitor useful in the treatment of cancer and processes of making said hemifumarate.
公开/授权文献
- US07244736B2 Tubulin inhibitor and process for its preparation 公开/授权日：2007-07-17
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