发明申请
US20060287357A1 Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
有权
三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
- 专利标题: Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
- 专利标题(中): 三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
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申请号: US11448947申请日: 2006-06-07
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公开(公告)号: US20060287357A1公开(公告)日: 2006-12-21
- 发明人: James Li , Lawrence Hamann , Haixia Wang , Zheming Ruan , Christopher Cooper , Jun Li , Jeffrey Robl
- 申请人: James Li , Lawrence Hamann , Haixia Wang , Zheming Ruan , Christopher Cooper , Jun Li , Jeffrey Robl
- 主分类号: A61K31/4745
- IPC分类号: A61K31/4745 ; C07D471/02
摘要:
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L, R3, R3a, R3b and R4 are defined herein.
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