- 专利标题： Fusion proteins of mycobacterium tuberculosis antigens and their uses
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申请号： US11511587申请日： 2006-08-28
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公开(公告)号： US20060292169A1公开(公告)日： 2006-12-28
- 发明人: Steven Reed , Yasir Skeiky , Davin Dillon , Mark Alderson , Antonio Campos-Neto
- 申请人： Steven Reed , Yasir Skeiky , Davin Dillon , Mark Alderson , Antonio Campos-Neto
- 申请人地址： US WA Seattle
- 专利权人： Corixa Corporation
- 当前专利权人： Corixa Corporation
- 当前专利权人地址： US WA Seattle
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K39/02 ; A61K39/04 ; C07K14/35
摘要：
The present invention relates to fusion proteins containing at least two Mycobacterium tuberculosis antigens. In particular, it relates to bi-fusion proteins which contain two individual M. tuberculosis antigens, tri-fusion proteins which contain three M. tuberculosis antigens, tetra-fusion proteins which contain four M. tuberculosis antigens, and penta-fusion proteins which contain five M. tuberculosis antigens, and methods for their use in the diagnosis, treatment and prevention of tuberculosis infection.
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