发明申请
- 专利标题: WATER SOLUBLE ANALGESIC FORMULATIONS AND METHODS FOR PRODUCTION
- 专利标题(中): 水可溶性制剂及其生产方法
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申请号: US11424560申请日: 2006-06-16
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公开(公告)号: US20060292225A1公开(公告)日: 2006-12-28
- 发明人: Arthur FELIX , Robert Martin
- 申请人: Arthur FELIX , Robert Martin
- 主分类号: A61K31/60
- IPC分类号: A61K31/60 ; A61K9/14
摘要:
A water soluble analgesic composition includes a plurality of granules. Each of the granules includes a substrate core and a coating disposed on the substrate core forming an agglomerated product, the coating including a salt of an analgesic, but substantially no particles of a non-salt form of the analgesic. The composition may be created by a method including the steps of: (i) providing a first solution comprising a base, (ii) adding an analgesic to the first solution to create a second solution including a salt of the analgesic, (iii) filtering the second solution to remove residual particles of the analgesic to create a filtered second solution, and (iv) spray drying the filtered second solution onto a substrate to form an agglomerated product having a plurality of granules.
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