发明申请
US20070004803A1 Compounds and methods for use in treating neoplasia and cancer based upon inhibitors of isoprenylcysteine methyltransferase
审中-公开
基于异戊二烯基半胱氨酸甲基转移酶抑制剂治疗肿瘤和癌症的化合物和方法
- 专利标题： Compounds and methods for use in treating neoplasia and cancer based upon inhibitors of isoprenylcysteine methyltransferase
- 专利标题（中）： 基于异戊二烯基半胱氨酸甲基转移酶抑制剂治疗肿瘤和癌症的化合物和方法
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申请号： US10552754申请日： 2004-03-26
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公开(公告)号： US20070004803A1公开(公告)日： 2007-01-04
- 发明人: Richard Gibbs , Brian Henriksen , Christine Hrycyna , Jessica Anderson
- 申请人： Richard Gibbs , Brian Henriksen , Christine Hrycyna , Jessica Anderson
- 申请人地址： US IN West Lafayette 47906
- 专利权人： Purdue Research Foundation
- 当前专利权人： Purdue Research Foundation
- 当前专利权人地址： US IN West Lafayette 47906
- 国际申请： PCT/US04/09506 WO 20040326
- 主分类号： A61K31/198
- IPC分类号： A61K31/198 ; C07C323/39
摘要：
The present invention relates to a novel method for the treatment of neoplasia, including cancer and other diseases and conditions in humans and mammals. More particularly, in preferred aspects, the present invention provides a method for the use of prenylcysteine analogs for the treatment of neoplasia, hyperproliferative cell growth including psoriasis, restenosis following cardiovascular surgery, hyperplasia, including renal hyperplasia, chronic inflammatory diseases including rheumatoid and osteoarthritis, among others.
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