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1.发明申请Compounds and methods for use in treating neoplasia and cancer based upon inhibitors of isoprenylcysteine methyltransferase 审中-公开基于异戊二烯基半胱氨酸甲基转移酶抑制剂治疗肿瘤和癌症的化合物和方法公开(公告)号：US20070004803A1
公开(公告)日：2007-01-04
申请号：US10552754
申请日：2004-03-26
IPC分类号： A61K31/198 , C07C323/39
CPC分类号： C07C323/59 , C07C2601/14 , C07C2603/74
摘要： The present invention relates to a novel method for the treatment of neoplasia, including cancer and other diseases and conditions in humans and mammals. More particularly, in preferred aspects, the present invention provides a method for the use of prenylcysteine analogs for the treatment of neoplasia, hyperproliferative cell growth including psoriasis, restenosis following cardiovascular surgery, hyperplasia, including renal hyperplasia, chronic inflammatory diseases including rheumatoid and osteoarthritis, among others.
摘要翻译： 本发明涉及一种用于治疗包括癌症和其他疾病和病症在人类和哺乳动物中的瘤形成的新方法。 更具体地说，在优选方面，本发明提供了一种使用异戊烯基半胱氨酸类似物用于治疗瘤形成，包括牛皮癣在内的过度增殖细胞生长，心血管手术后的再狭窄，包括肾增生，包括类风湿和骨关节炎在内的慢性炎性疾病， 等等
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