发明申请
- 专利标题： Therapeutic isoquinoline compounds
- 专利标题（中）： 治疗异喹啉化合物
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申请号： US10494424申请日： 2002-11-01
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公开(公告)号： US20070010526A1公开(公告)日： 2007-01-11
- 发明人: Markus Haeberlein , Christof Angst , Daniel Hill , Robert Jacobs , Gary Moore , Edward Pierson , Ashokkumar Shenvi
- 申请人： Markus Haeberlein , Christof Angst , Daniel Hill , Robert Jacobs , Gary Moore , Edward Pierson , Ashokkumar Shenvi
- 优先权： SE0103644-1 20011101
- 国际申请： PCT/SE02/01988 WO 20021101
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/4709 ; C07D403/02 ; C07D401/02
摘要：
Provided herein is a compound of the formula (I), wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety, eating disorders, dementia, panic disorder, and sleep disorders. The compounds may also be useful in the treatment of gastrointestinal disorders, cardiovascular regulation, motor disorders, endocrine disorders, vasospasm and sexual dysfunction. The compounds are 5HT1B and 5HT1D antagonists.