发明申请
US20070020671A1 Method for detecting large mutations and duplications using control amplification comparisons to paralogous genes
审中-公开
使用对旁系同源基因的对照扩增比较检测大突变和重复的方法
- 专利标题： Method for detecting large mutations and duplications using control amplification comparisons to paralogous genes
- 专利标题（中）： 使用对旁系同源基因的对照扩增比较检测大突变和重复的方法
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申请号： US11485167申请日： 2006-07-12
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公开(公告)号： US20070020671A1公开(公告)日： 2007-01-25
- 发明人: Ray Radtkey , Douglas Whitman , Graham Lidgard
- 申请人： Ray Radtkey , Douglas Whitman , Graham Lidgard
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34
摘要：
Methods for querying biological samples to detect genetic mutations, particularly insertions and deletions, by co-amplification of a gene of interest in conjunction with a paralogous gene. When the gene of interest and the corresponding paralogous gene are selected from the CYP450 family, the resulting ratios may predict how a particular patient metabolizes certain prescription drugs.
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