The present invention is a method and device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart, and related methods of using such closure devices for closing the passageway. The closure device includes a closure line having a first and a second end. A first expandable device is connected to the first end of the closure line. A second expandable device is located along the second end of the closure line, and is capable of sliding along the closure line in one direction while preventing sliding movement in the opposite direction. Alternatively the second closure line is fixed along the second end of the closure line.