发明申请
US20070037745A1 Nucleic acid and corresponding protein entitled 213P1F11 useful in treatment and detection of cancer
失效
核酸和相应的蛋白质213P1F11可用于治疗和检测癌症
- 专利标题: Nucleic acid and corresponding protein entitled 213P1F11 useful in treatment and detection of cancer
- 专利标题(中): 核酸和相应的蛋白质213P1F11可用于治疗和检测癌症
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申请号: US11090545申请日: 2005-03-25
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公开(公告)号: US20070037745A1公开(公告)日: 2007-02-15
- 发明人: Pia Challita-Eid , Arthur Raitano , Mary Faris , Rene Hubert , Robert Morrison , Wangmao Ge , Aya Jakobovits
- 申请人: Pia Challita-Eid , Arthur Raitano , Mary Faris , Rene Hubert , Robert Morrison , Wangmao Ge , Aya Jakobovits
- 主分类号: A01K67/00
- IPC分类号: A01K67/00 ; A61K39/395 ; C12N5/06 ; C07K14/82 ; C07K16/18
摘要:
A novel gene (designated 213P1F11) and its encoded protein, and variants thereof, are described wherein 213P1F11 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 213P1F11 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 213P1F11 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 213P1F11 can be used in active or passive immunization.
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