发明申请
US20070037823A1 Substituted piperidine and piperazine derivatives as melanocortin-4 receptor modulators
审中-公开
取代的哌啶和哌嗪衍生物作为黑皮质素-4受体调节剂
- 专利标题： Substituted piperidine and piperazine derivatives as melanocortin-4 receptor modulators
- 专利标题（中）： 取代的哌啶和哌嗪衍生物作为黑皮质素-4受体调节剂
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申请号： US10549942申请日： 2004-03-19
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公开(公告)号： US20070037823A1公开(公告)日： 2007-02-15
- 发明人: Michael Soeberdt , Philipp Weyermann , Andreas Von Sprecher , Marco Hennebohle
- 申请人： Michael Soeberdt , Philipp Weyermann , Andreas Von Sprecher , Marco Hennebohle
- 优先权： EP03006256.6 20030320
- 国际申请： PCT/EP04/02896 WO 20040319
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/4709 ; A61K31/353
摘要：
The present invention relates to novel substituted piperidine and piperazine derivatives as melanocortin-4 receptor (MC-4R) modulators. MC-4R agonists of the invention can be used for the treatment of disorders and diseases such as obesity, diabetes and sexual dysfunction, whereas the MC-4R antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, anxiety and depression. All diseases and disorders, where the regulation of the MC-4R is involved, can be treated with the compounds of the invention.
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