发明申请
- 专利标题： Thiazolypiperidine derivatives as mtp inhibitors
- 专利标题（中）： 噻唑基哌啶衍生物作为mtp抑制剂
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申请号： US10561989申请日： 2004-06-02
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公开(公告)号： US20070054939A1公开(公告)日： 2007-03-08
- 发明人: Philippe Guedat , Francois Collonges , Herve Dumas , Jean-Yves Ortholand , Jacques Decerprit , Jaxques Barbanton , Robert Foster , Peter Kane , Bernd Went
- 申请人： Philippe Guedat , Francois Collonges , Herve Dumas , Jean-Yves Ortholand , Jacques Decerprit , Jaxques Barbanton , Robert Foster , Peter Kane , Bernd Went
- 优先权： FR03/07670 20030625
- 国际申请： PCT/EP04/05931 WO 20040602
- 主分类号： A61K31/4545
- IPC分类号： A61K31/4545 ; A61K31/454 ; C07D417/14
摘要：
The present invention relates to thiazolylpiperidine derivatives of the general formula (I): in which: A represents a radical chosen from the radicals a1 and a2 below: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3 below: and R1, R2, R2′, R3, R4, R5, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hypertriglyceridaemia, hypercholesterolaemia and dyslipidaemia.
公开/授权文献
- US07674803B2 Thiazolypiperidine derivatives as MTP inhibitors 公开/授权日：2010-03-09
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