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发明申请
US20070071755A1 Novel nucleolar GTPases and method for controlling proliferation of cells 审中-公开
新型核仁GTPases和细胞增殖抑制方法

Novel nucleolar GTPases and method for controlling proliferation of cells
摘要：
There is provided an isolated polypeptide comprising an amino acid sequence at least 85% homologous to SEQ ID NO: 2 or SEQ ID N: 4, or a conservative variant thereof, wherein the polypeptide regulates proliferation of a cell. There is also provided an isolated polynucleotide encoding the polypeptide of the invention. There is also provided a method for inhibiting the proliferation of a cell, comprising altering the level of a polypeptide comprising an amino acid sequence at least 85% homologous to SEQ ID NO: 2 or SEQ ID NO: 4 in the cell, thereby inhibiting proliferation of the cell.
摘要（中）：

提供了分离的多肽，其包含与SEQ ID NO：2或SEQ ID NO：4或其保守变体至少85％同源的氨基酸序列，其中所述多肽调节细胞的增殖。 还提供了编码本发明多肽的分离的多核苷酸。 还提供了抑制细胞增殖的方法，包括改变包含与细胞中SEQ ID NO：2或SEQ ID NO：4至少85％同源的氨基酸序列的多肽的水平，由此抑制增殖 的细胞。

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