Invention Application
- Patent Title: Constitutively activated human G protein coupled receptors
- Patent Title (中): 组成性激活人类G蛋白偶联受体
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Application No.: US11603356Application Date: 2006-11-21
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Publication No.: US20070072248A1Publication Date: 2007-03-29
- Inventor: Ruoping Chen , Chen Liaw , Kevin Lowitz , Derek Chalmers , Dominic Behan
- Applicant: Ruoping Chen , Chen Liaw , Kevin Lowitz , Derek Chalmers , Dominic Behan
- Applicant Address: US CA San Diego 92121
- Assignee: Arena Pharmaceuticals, Inc.
- Current Assignee: Arena Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego 92121
- Main IPC: G01N33/567
- IPC: G01N33/567 ; A61K38/55
Abstract:
The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown (“orphan GPCR receptors”), and most particularly to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.
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