发明申请
US20070072918A1 Benzothiadiazolylphenylalkylamine derivatives and methods of their use
失效
苯并噻二唑基苯基烷基胺衍生物及其使用方法
- 专利标题： Benzothiadiazolylphenylalkylamine derivatives and methods of their use
- 专利标题（中）： 苯并噻二唑基苯基烷基胺衍生物及其使用方法
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申请号： US11528792申请日： 2006-09-27
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公开(公告)号： US20070072918A1公开(公告)日： 2007-03-29
- 发明人: Casey McComas , Puwen Zhang , Eugene Trybulski , An Vu , Eugene Terefenko
- 申请人： Casey McComas , Puwen Zhang , Eugene Trybulski , An Vu , Eugene Terefenko
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： C07D275/04
- IPC分类号： C07D275/04 ; C07D271/12 ; A61K31/433 ; A61K31/425
摘要：
The present invention is directed to benzothiadiazolylphenylalkylamine derivatives of formula I: or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.