发明申请
- 专利标题: Novel piperidine derivative
- 专利标题(中): 新型哌啶衍生物
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申请号: US10576581申请日: 2004-10-19
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公开(公告)号: US20070078120A1公开(公告)日: 2007-04-05
- 发明人: Hitoshi Ban , Satoshi Ohnuma , Norie Tsuboya , Shigehiro Asano
- 申请人: Hitoshi Ban , Satoshi Ohnuma , Norie Tsuboya , Shigehiro Asano
- 优先权: JP2003-361256 20031021
- 国际申请: PCT/JP04/15773 WO 20041019
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; A61K31/4545 ; A61K31/397
摘要:
The invention provides a compound of the following formula (1): wherein m, n, and p are independently an integer of 0-4, provided 3≦m+n≦8; X is nitrogen atom or a group of the formula: C—R15; Y is a substituted or unsubstituted aromatic group, etc.; R15, R1, R2, R3, R4, R5, R6 and R7 are hydrogen atom, a substituted or unsubstituted alkyl group, etc.; and Z is hydrogen atom, cyano group, etc., or a prodrug thereof, or a pharmaceutically acceptable salt thereof, which exhibits an action for enhancing LDL receptor expression, and is useful as a medicament for treating hyperlipidemia, atherosclerosis, etc.
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