- 专利标题: Quinazoline derivatives as antitumor agents
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申请号: US11443208申请日: 2006-05-31
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公开(公告)号: US20070082921A1公开(公告)日: 2007-04-12
- 发明人: Laurent Hennequin , Jason Kettle , Martin Pass , Robert Bradbury
- 申请人: Laurent Hennequin , Jason Kettle , Martin Pass , Robert Bradbury
- 专利权人: ASTRAZENECA AB
- 当前专利权人: ASTRAZENECA AB
- 优先权: GB0126433.2 20011103; GB0129059.2 20011205
- 主分类号: A61K31/517
- IPC分类号: A61K31/517 ; C07D403/02
摘要:
The invention concerns quinazoline derivatives of Formula (I); wherein each of Q , Q , Z, R , R , R , and m have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosin kinases.
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