Invention Application
US20070087331A1 Selection of b cells with specificity if interest: method of preparation and use
审中-公开
选择具有特异性的b细胞，如果兴趣：准备和使用方法
- Patent Title: Selection of b cells with specificity if interest: method of preparation and use
- Patent Title (中): 选择具有特异性的b细胞，如果兴趣：准备和使用方法
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Application No.: US10556904Application Date: 2004-05-14
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Publication No.: US20070087331A1Publication Date: 2007-04-19
- Inventor: Martin Bachmann , Dominique Gatto
- Applicant: Martin Bachmann , Dominique Gatto
- Applicant Address: CH Zurich-Schlieren CH-8952
- Assignee: Cytos Biotechnology AG
- Current Assignee: Cytos Biotechnology AG
- Current Assignee Address: CH Zurich-Schlieren CH-8952
- International Application: PCT/EP04/05208 WO 20040514
- Main IPC: C12Q1/70
- IPC: C12Q1/70 ; C12N5/20 ; G01N33/567
Abstract:
The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides methods using a composition comprising an ordered and repetitive antigen or antigenic determinant array for visualization and selection of B cells specific for the antigen. These B cells are useful for the production of monoclonal antibodies used for therapy, diagnostic or research purposes.
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