发明申请
- 专利标题: Quinazoline derivatives as antitumor agents
- 专利标题(中): 喹唑啉衍生物作为抗肿瘤剂
-
申请号: US11443395申请日: 2006-05-31
-
公开(公告)号: US20070088044A1公开(公告)日: 2007-04-19
- 发明人: Laurent Hennequin , Jason Kettle , Martin Pass , Robert Bradbury
- 申请人: Laurent Hennequin , Jason Kettle , Martin Pass , Robert Bradbury
- 专利权人: ASTRAZENECA AB
- 当前专利权人: ASTRAZENECA AB
- 优先权: GB0126433.2 20011103
- 主分类号: A61K31/517
- IPC分类号: A61K31/517 ; C07D403/02 ; C07D239/94
摘要:
The invention concerns quinazoline derivatives of Formula (I); wherein each of Q , Q , Z, R , R , R , and m have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosin kinases.