发明申请
- 专利标题： Membrane-permeable NFAT inhibitory peptide
- 专利标题（中）： 膜透性NFAT抑制肽
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申请号： US11633529申请日： 2006-12-05
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公开(公告)号： US20070093427A1公开(公告)日： 2007-04-26
- 发明人: Hideki Matsui , Masayuki Matsushita
- 申请人： Hideki Matsui , Masayuki Matsushita
- 申请人地址： JP Kawaguchi-shi JP Okayama-shi JP Kurashiki-shi
- 专利权人： JAPAN SCIENCE AND TECHNOLOGY AGENCY,MATSUI HIDEKI,MATSUSHITA MASAYUKA
- 当前专利权人： JAPAN SCIENCE AND TECHNOLOGY AGENCY,MATSUI HIDEKI,MATSUSHITA MASAYUKA
- 当前专利权人地址： JP Kawaguchi-shi JP Okayama-shi JP Kurashiki-shi
- 优先权： JP2002-54912 20020228
- 主分类号： A61K38/10
- IPC分类号： A61K38/10 ; A61K38/08 ; C07K7/08
摘要：
The present invention aims to solve the conventional problems by providing a peptide compound, in which when administered to a patient of immunologic disease, cardiac hypertrophy or a disease caused by NFAT activation, the period from administration to actual exhibition of effectiveness is short and there are no side effects or antigenicity. Specifically, the present invention relates to a membrane permeable NFAT inhibitory peptide comprising several consecutive arginines and a NFAT-activity inhibitory peptide sequence; a NFAT activation inhibitory agent comprising the peptide; and a immunosuppressive agent and cardiac hypertrophy suppressive agent, comprising the peptide compound as the active ingredient.
公开/授权文献
- US07659249B2 Membrane-permeable NFAT inhibitory peptide 公开/授权日：2010-02-09
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