发明申请
US20070099974A1 (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1(pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition
有权
（R）-2-（4-脒基苯基氨基甲基）-1-甲基-5- [1-（羧甲基氨基）-1-（吡咯烷基羰基） - 乙基] - 苯并咪唑，其一盐酸盐，其制备和用作药物组合物
![(R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1(pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition](/docs/US/2007-05-03/US20070099974A1/abs.jpg.600x600.jpg)
- 专利标题： (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1(pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition
- 专利标题（中）： （R）-2-（4-脒基苯基氨基甲基）-1-甲基-5- [1-（羧甲基氨基）-1-（吡咯烷基羰基） - 乙基] - 苯并咪唑，其一盐酸盐，其制备和用作药物组合物
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申请号： US11610187申请日： 2006-12-13
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公开(公告)号： US20070099974A1公开(公告)日： 2007-05-03
- 发明人: Guenter Linz , Peter Sieger , Gunnar Schreiner , Werner Rall , Rolf Schmid
- 申请人： Guenter Linz , Peter Sieger , Gunnar Schreiner , Werner Rall , Rolf Schmid
- 优先权： DE10227666.8 20020620
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; C07D403/02
![(R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1(pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition](/abs-image/US/2007/05/03/US20070099974A1/abs.jpg.150x150.jpg)
摘要：
Crystalline forms of the compounds (R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1 -(carboxymethylamino)-1-(pyrrolidinocarbonyl)-ethyl]-benzimidazole and the monohydrochloride thereof, processes for the preparation thereof and the use thereof as pharmaceutical compositions.
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